Suyash P. Awate |
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Brain Tissue Segmentation via MRI |
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| Suyash P. Awate, Tolga Tasdizen, Normal Foster, Ross T. Whitaker Adaptive Markov modeling for mutual-information-based, unsupervised MRI brain-tissue classification Medical Image Analysis 2006, 10(5):726-39 (invited paper from MICCAI 2005 conference) |
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| Challenges | Strategy |
| (1) noise | (1) Markov random field model on data inferred nonparametrically |
| (2) oversmoothing in cortex | (2) avoid explicit label regularization |
| (3) RF-field bias / inhomogeneity / nonuniformity | (3) spatially-adaptive tissue modeling |
| (4) partial-volume effects | (4) nonparametric modeling |
| (5) speed | (5) approximations in statistical estimation: takes 5 minutes for BrainWeb image |
| Robustness to noise and partial-volume effects | |
| BrainWeb Data in graph: solid line = proposed method ![]() |
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| Robustness to RF-field bias / inhomogeneity / nonuniformity | |
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| Validation for segmenting tissues : IBSR Repository from MGH | |
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| Validation for delineating the inner cortical-surface | |
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Related Work |
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| M. Yan and J. Karp An adaptive Bayesian approach to three-dimensional MR brain segmentation In Proc. Information Processing in Medical Imaging 1995, pp. 201-213 |
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| T. Kapur, W. E. L. Grimson, W. M. Wells, and R. Kikinis Segmentation of brain tissue from magentic resonance images Medical Image Analysis 1996, 1:109-127 |
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| W. M. Wells, W. E. L. Grimson, R. Kikinis, and F. A. Jolesz Adaptive segmentation of MRI data IEEE Trans. Medical Imaging 1996, 15(4):429-443 |
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| K. V. Leemput, F. Maes, D. Vandermeulen, and P. Seutens Automated model-based tissue classification of MR images of the brain IEEE Trans. Med. Imaging 1999, 18:897-908 |
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| D. L. Pham, J. L. Prince An adaptive fuzzy segmentation algorithm for three-dimensional magnetic resonance images Proc. Information Processing in Medical Imaging 1999, pp. 140-153 |
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| Y. Zhang, M. Brady, and S. Smith Segmentation of brain MR images through a hidden Markov random field model and the expectation maximization algorithm IEEE Trans. Med. Imaging 2001, 20:45-57 |
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| H. Greenspan, A. Ruf , J. Goldberger Constrained Gaussian mixture model framework for automatic segmentation of MR brain images IEEE Trans. Med. Imaging 2006, 25(9):1233-1245 |
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| Suyash P. Awate, Hui Zhang , James C. Gee A Fuzzy, Nonparametric Segmentation Framework for DTI and MRI Analysis: With Applications to DTI-Tract Extraction IEEE Trans. Medical Imaging 2007, 26(11):1525-1536 |
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