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Slide 3 of 42

... trial and error! Or at least how its done most of the time now - because the parameter space of all possible transfer functions is just too large, and nothing about the usual interface for setting the transfer function is at all constrained by the underlying data. So there's little intuitive relationship between an adjustment made to the transfer function and the resulting change in the image. For example, the goal here was to visualize the skin surface, and you can see that it took a few tries to get it right.